Propionate kinase
Propionate kinase (EC 2.7.2.15, PduW, TdcD, Propionate / acetate kinase) là một enzym có tên hệ thống ATP: phosphotransferase propanoate.[1][2][3][4][5][6] Enzyme này xúc tác phản ứng hóa học sau:
Propionate kinase | |||||||||
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Mã định danh (ID) | |||||||||
Mã EC | 2.7.2.15 | ||||||||
Mã CAS | 39369-28-3 | ||||||||
Các dữ liệu thông tin | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | chu trình chuyển hóa | ||||||||
PRIAM | profile | ||||||||
Các cấu trúc PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
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- ATP + propanoate ADP + propanoyl phosphate
Enzym này đòi hỏi Mg2+.
Tham khảo
sửa- ^ Heßlinger, C.; Fairhurst, S.A.; Sawers, G. (1998). “Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate”. Mol. Microbiol. 27: 477–492. doi:10.1046/j.1365-2958.1998.00696.x. PMID 9484901.
- ^ Palacios, S.; Starai, V.J.; Escalante-Semerena, J.C. (2003). “Propionyl coenzyme A is a common intermediate in the 1,2-propanediol and propionate catabolic pathways needed for expression of the prpBCDE operon during growth of Salmonella enterica on 1,2-propanediol”. J. Bacteriol. 185: 2802–2810. doi:10.1128/jb.185.9.2802-2810.2003. PMC 154405. PMID 12700259.
- ^ Wei, Y.; Miller, C.G. (1999). “Characterization of a group of anaerobically induced, fnr-dependent genes of Salmonella typhimurium”. J. Bacteriol. 181: 6092–6097. PMC 103637. PMID 10498722.
- ^ Ingram-Smith, C.; Gorrell, A.; Lawrence, S.H.; Iyer, P.; Smith, K.; Ferry, J.G. (2005). “Characterization of the acetate binding pocket in the Methanosarcina thermophila acetate kinase”. J. Bacteriol. 187: 2386–2394. doi:10.1128/jb.187.7.2386-2394.2005. PMC 1065240. PMID 15774882.
- ^ Simanshu, D.K. (2005). “Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of propionate kinase (TdcD) from Salmonella typhimurium”. Acta Crystallogr. F. 61: 52–55. doi:10.1107/s1744309104026429. PMC 1952409. PMID 16508089.
- ^ Simanshu, D.K.; Savithri, H.S.; Murthy, M.R. (2005). “Crystal structures of ADP and AMPPNP-bound propionate kinase (TdcD) from Salmonella typhimurium: comparison with members of acetate and sugar kinase/heat shock cognate 70/actin superfamily”. J. Mol. Biol. 352: 876–892. doi:10.1016/j.jmb.2005.07.069. PMID 16139298.